The number of discrete velocities is not fixed in the present model because the speed rate can be truncated arbitrarily.
"We're here because we don't like the present model of development," said Anna Lazarotti, a Genoa homemaker and mother of one, who came with about 40 members of her women's club, the Baghdad Cafe.
The maximum value of τ on the interplate megathrust was not well constrained in the present model because of the uncertainty in rheological parameters in the brittle-ductile transition zone and pore pressure distributions.
For cases 1 and 3 at p tot = 1 bar, the costs are completely governed by the pure gas prices in the present model, because in- and outside pressures are equal and friction and hydraulic pressure are neglected.
The semi-empirical flow law of Hirth et al. (2001) was, however, not used in the present model because the tectonic setting, grain size, and water contents of the quartzite samples are far different from those of chert in subduction zones.
Although Hutchinson [58] and Huston [59] argued for enhanced diversity at environmentally dynamic localities, because competitive displacement is prevented, the present model predicts that several Symbiodinium populations are likely to be present in locations where the physical environment is benign.
This cost was not included in the present model because it is not clear how to define it rigorously.
Heterodimers were neglected in the present model because the cell line utilized in this study exhibited an insignificant heterodimer population as a fraction of total receptors (Additional file 5) and inhibition of IR activity did not decrease IGF1-induced proliferation (Additional file 6); however, a more broadly applicable model may need to include their effect.
However, after direct stimulation of PKC by PMA treatment the elevation of p21 expression has been reported in a p53-independent manner [ 46, 47], which may support the present model because of the non-functional p53 in the U937 cells line.
