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Single molecule time traces show multiple dsDNA binding and dissociation events to the same filament because the observed interactions are transient without forming a stable product.
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In addition, it is difficult to distinguish the effects of dietary fat and carbohydrate responsible for the observed interactions because the high-fat diets have low carbohydrate content.
The observed interactions are specific, as H2A nucleosomes failed to interact with these two factors.
These observations suggest that the PD and HD of Ey are critical for the observed interactions.
The observed interactions provide new insights to future inhibitor designs.
Ultimately, these methods were not designed to evaluate the strength of the observed interactions.
These tests demonstrated the credibility of the observed interactions of each clone group.
It thus appears improbable that misclassification should be responsible for the observed interactions.
[3 min] The observed interactions underscored a number of the key points arising from interviews.
However, more efforts are required to elucidate the exact mechanisms that define the observed interactions.
Two explanations for the observed interactions in Study 1 were considered.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com