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Because the major function of FA proteins is to repair ICL lesions, we next tested whether ICL agents can induce centrosome amplification.
The effect of miRNAs on their targets is reflected by the anti-correlated expression patterns between miRNAs and their mRNA targets because the major function of plant miRNAs is mRNA cleavage.
Because the major function of FA proteins is to repair ICL lesions and we found that FancJ has a role in regulating the normal centrosome cycle, as well as HU-induced centrosome amplification (Fig. 2C E; supplementary material Fig. S4C), we hypothesized that FancJ connects the ICL response to centrosome amplification.
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However, cellular iron uptake may not be the major function of TfR2, because both human and mouse mutations in TfR2 as well as the mouse knockout lead to increased rather than decreased levels of liver iron deposition.
The major function of sclerenchyma is support.
And the major function of Oscar night is to affirm that gauzy, enchanting notion.
The major function of apoE is participating in cholesterol homeostasis.
Still other proposals made housing specialized organs the major function.
The major function of ChREBP is the regulation of lipogenesis.
Facility cores are the major function of the EHS Core Center.
Because one of the major functions of mitochondria is oxidative phosphorylation (OxPhos), we analyzed the expression of OxPhos genes.
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