Sentence examples for because the insertional effects from inspiring English sources

Because the insertional effects are still unclear, the relevant studies are needed in the future.

As with the R111G Tg mice, the absence of phenotypes in the R306C Tg mice demonstrates that the phenotypes observed in the R306C mice are caused by the mutation and not insertional effects of the transgene.

Given that the splenomegaly phenotype was apparent in only one line however, we cannot completely exclude the possibility that insertional effects generate this phenotype.

Reduced monocyte numbers were observed in independent Slfn4 transgenic lines, indicating that the phenotype was unlikely to arise from insertional effects of the transgene.

Because the insertional mutagen's sequence is known, techniques that amplify adjacent genomic regions for sequencing can readily be implemented.

We therefore cannot completely exclude that this particular phenotype arises from an insertional effect of the transgene, but this would seem unlikely because the monocytopoiesis defect was apparent in multiple independent lines, and because various Slfn family members have been shown to regulate immune cell development and/or survival.

This precaution is necessary to avoid erroneously attributing a phenotype, caused by an insertional effect on endogenous mouse genes, to the transgene itself.

The aim of the present study was therefore to estimate the effects of the insertional speed of electrode insertion on ICFP in a cochlear model.

The use of insulators helps overcome the influence of insertional position effects on transcriptional response, ensuring more homogeneous basal levels of expression of the transgene.

Because the HoxD cluster remained entirely untouched by the insertional events, we investigated whether these phenotypes were induced by regulatory modifications at a distance.

Because of the safety issues with viral vectors, including the insertional mutagenesis and potential tumor formation, non-viral transfection methods are preferred for clinical translation.