Sentence examples for because the functional consequences from inspiring English sources

However, there remains a fundamental problem because the functional consequences of abnormalities detected with such high-resolution imaging technology are unclear.

Coding regions are targeted because the functional consequences of variants in these regions are much better understood than those in noncoding parts of the genome.

Interpretation of differential DNA-methylation patterns in cancer has proven difficult, in part because the functional consequences depend on the genomic region involved, the specific CpG dinucleotides, and the inter- and intratumoral heterogeneity.

The concept of positional orthology is important because of the functional consequences of genomic context.

Because extensive studies of the functional consequences of presumed direct interaction of Src with Na+/K+-ATPase have been reported, it was important to explore the functional status of the endogenous Src of the two kidney pools of the Na+/K+-ATPase.

However, these traditional indices are probably most useful when they are evaluated in combination with other indices that provide information about differences in species identity among treatments or plots, particularly because species identity often dictates the functional consequences of diversity (Díaz et al. 2003; Olden et al. 2004).

Several previous studies have used conservation scores, which are derived from evolutionary comparisons, in estimating the functional importance of such SNPs (Chorley et al. 2008; Goode et al. 2010; Montgomery et al. 2011; Maurano et al. 2012; Kircher et al. 2014) because it is difficult to quantify the functional consequences of noncoding or synonymous SNPs.

Combining bioinformatic programs can be helpful in predicting the functional consequences of CVs because it improved the performance of functional predictions.

Our approach initially involved determining the functional significance of the common SULT1A1*2 allozyme toward E2 because, unlike UGT1A1, little has previously been reported regarding the functional consequences of genetic variation of SULT1A1 toward E2 biology.

To investigate the functional consequences of succination, we focused on ACO2 because of its role in the Krebs cycle, where it catalyzes the stereospecific isomerization of citrate to isocitrate via cis-aconitate.

Because of their transparency, severe morphological abnormalities in cardiac development are easily observed, but the functional consequences of these defects are difficult to quantify.