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This adjustment was required because the expected proportion of observed unmethylated copies is dependent on the ratio of unmethylated somatic copies to tumor copies at the BRCA1 locus.
However, because the expected proportion of the genome shared is 2 R = (d−1), the mean total length shared is actually l(d−1).
This is because the expected proportion of unique records in a sample will be the same as the proportion of unique records in the population [ 54].
Sl-CSD is a form of inbreeding depression, because the expected proportion of unfit diploid males is higher in the offspring of genetically related parents (e.g. 12.5% in the progeny of full siblings).
Similar(56)
by the expected proportion value.
The thresholds were set at: 1) the exact proportion for the mutation expected; 2) 75%% of the expected proportion; and 3) 50%% of the expected proportion.
We used an FDR correction, because it controls the expected proportion of incorrectly rejected null hypotheses (Benjamini and Hochberg, 1995).
The κ coefficients are calculated by considering the proportion of rater agreement and the expected proportion [17].
The expected proportion is 25%.
This second analysis sought to establish during which bins the observed proportion mismatched the expected proportion.
How were the expected proportions determined?
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