Sentence examples for because the dosing interval from inspiring English sources

In study 1, limited PK parameters were estimable because the dosing interval for MEDI-528 was not constant, alternating between 3 days and 4 days, and PK sampling was sparse.

The authors recommended a loading dose of 9 million IU and 4.5 million IU 12-hourly because colistin displayed a half-life that was significantly long in relation to the dosing interval.

Similarly, lengthening the dosing interval should be considered when codeine products are used because of retention of pharmacologically active metabolites, particularly after a few days of therapy have elapsed and metabolite serum concentrations increase.

maximum concentration within the dosing interval.

The dosing interval should be 4 hours to ensure anti-GBS activity in all patients.

Consequently, the dosing interval of per oral administration remains unknown.

For infliximab, this includes a decrease in the dosing interval.

The noncompartmental analysis was performed over the dosing interval, 21 days following the first dose.

The dosing interval has a default value of 24 hours, i.e. one dose per day, but this can be changed manually if another dosing interval is preferred.

In the 21 patients who did report breakthrough haemolysis, shortening the dosing interval to <14 d was sufficient to maintain inhibition of haemolysis, and none of these patients discontinued treatment because of a lack of therapeutic effect.

Firstly, the dose delivered per cycle can be increased (dose intensity), secondly, the dosing interval can be reduced keeping the dose per cycle and overall dose the same (dose densification), and finally both the dosing interval can be reduced and the overall dose increased (increased dose intensity, total dose, and dose density) [ 9].