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The age difference is primarily because the contemporary sample was designed to have proportionately more infants in the younger age regions where most items are located.
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17 Data for the contemporary sample came from the Office of National Statistics.
No data regarding marital status were available for the contemporary sample.
Men are in general more likely to commit suicide than women, and in the contemporary schizophrenia sample there was a twofold greater rate of male admissions than in the historical cohort, but the increased suicide rate in the contemporary sample does not stem from this source in that in the contemporary schizophrenia sample there was a greater proportion of female than male suicides.
Using census data from 1881, 1891, 1901 and 1911, we have accordingly standardised our incidence figures for the contemporary sample to the rates observed for the historical sample.
Because the sample sizes differed, we resampled 14 genotypes from the contemporary samples 10,000 times and estimated mean He.
Nine alleles were not detected in the contemporary samples compared to historical samples.
In the contemporary samples, error rates were estimated by re-genotyping a subset (22%) of the samples.
Allelic richness was higher in the historical samples compared to the contemporary samples, indicating a population contraction.
Allele lengths show some tendency to be smaller in historic samples and longer in the contemporary samples (Additional file 4).
A PCA suggested that the Cousin and Marianne museum samples formed two separate clusters, with the contemporary samples forming a separate third cluster (Fig. 2).
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