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Because substantial work has been done on M. lanceolata we have fractionated the extracts of L.sericea and have isolated bioactive compounds and tested their activity in vitro.
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"Substantial work has been done and important foundations have been laid," he said.
Substantial work has been done for the resource mining problem.
Substantial work has been performed by numerous investigators to address the correction factor issue.
Substantial works have been conducted in automatic web query classification.
Although substantial works have been made in this field, it remains some unsolved problems.
Substantial research work has been done towards botnet detection.
For instance, might a Mother Teresa who is bored by her substantial charity work have a significant existence because of it, even if she would have an even more significant existence if she were excited by it?
"There's substantial work that has got to take place," said David Luchsinger, Federal Hall's acting superintendent.
A substantial amount of research work has been done for the study of Bratu's problem.
A substantial amount of theoretical work has been invested in modelling structural masonry.
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