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Because sensitizing drives would have no effect in the absence of their associated molecule – and in some cases vice versa – they could grant very fine control over the geography and extent of population suppression with minimal ecological risk.
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Of note, Morsci et al. (2011) recently showed that male sexual drive in C. elegans depends on hermaphrodite self-reproductive status, because sensitized mutant males expressed more vigorous mating attempts with fog-2 mutant compared to wild-type hermaphrodites.
The mTOR inhibitors rapamycin, everolimus, and temsirolimus are of particular interest for breast cancer bone metastasis because they have positive actions on bone in addition to sensitizing tumors to hormonal therapy and trastuzumab.
"A Million Little Pieces" is important because it sensitized people to the human pain of addiction and brought that message into American homes where it had never before penetrated.
The concurrent chemoradiotherapy outperforms sequential therapies because chemotherapy sensitizes the tumor cells to radiation-induced killing and treatment; meanwhile the concurrent therapy avoids the repopulation of cancer cells which will occur during the course of sequential treatment (Lawrence et al. 2014).
Determining the effect of lncRNA-Smad7 on Smad7 expression will be an important topic for future analysis, because Smad7 sensitizes MCF7 cells to IRF1-induced apoptosis.
HAPs may exacerbate asthma because, once sensitized, individuals can respond to remarkably low concentrations, and irritants lower the bronchoconstrictive threshold to respiratory antigens.
Although the three strategies showed some degree of effectiveness, the first was preferred by the authors because it sensitizes staff to the nature of the problem of aggression and develops their knowledge, skills, and attitudes in managing this behavior.
Because improved local tumor control is a therapeutic goal for most cancers, various strategies for sensitizing tumors to radiation have been tested over the last 20 years [ 9- 13].
Because CGAs are designed to cover a broad spectrum of elderly patients' concerns in different areas of life, they seem particularly suitable for sensitizing medical students to the complexity of the field.
Alpha factor is a 13 amino acid pheromone secreted by yeast cells of the alpha mating type in the presence of yeast cells of the opposite a mating type; a cells arrest in the presence of alpha factor because they express the sensitizing alpha-factor receptor STE2.
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