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Serum is a preferred specimen for the early diagnosis of malignant tumors, because samples are available readily by less invasive methods.
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The P-value on the test set is reduced because fewer samples are available.
Also it cannot predict the interaction between a new drug (without linking to any known target) and a new target (without linking to any known drug) because no positive samples are available to train its classifier model.
Covariance-based methods, in particular, often fail to detect subtle but discriminating features in the spectra even when enough training samples are available, because they are limited to working with first and second order statistics, while hyperspectral imagery is typically far from being Gaussian.
Samples are available now.
These genera were chosen because tissue samples were available that maximized the total percent coverage of species within each genus (7 out of 13 Dioon, 44 out of 65 Encephalartos).
Because bile samples were available only from animals with negative HEV RNA liver samples, no bile sample was positive for HEV RNA.
Because all samples were available only from fatal cases for children <5 years of age, we initially excluded these samples from biomarker statistical analyses.
We used the subset of radon measurements taken between 1 January 1989 and 31 December 2013 in our analysis because few samples were available from earlier years (n = 4,294).
Unfortunately, we could not compare MRP2 expression levels in cancer tissues from the same patient before and after NACT because no samples were available.
The other drugs were cytarabine in 12 (18 or 24 g/m), etoposide in 5 (400 mg/m), methotrexate in 4 and vincristine in 5. Fifteen other boys and 11 girls were excluded because no samples were available for measuring inhibin B. Their characteristics were similar to those who were included.
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