However, we contend that the earliest components are most relevant for the observed phase locking of first spikes because, according to our model, only the first excitatory change in neural excitability, which is reflected by the first negative slope of the LFP modulation, is crucial for generating the phase locking of the first spikes.
Because of these assumptions mentioned above, our model only needs to include the reaction rate constants shown in Figure 1I, which are k0, k−0, k1, k−1, k2, k−2, and k3.
Our 3-D model framework was chosen over a 1-D diffusive model39 because our model not only includes the vertical diffusion processes of 39 but also permits to follow the fate of the water masses 3-dimensionally as obviously observed off the hydrothermal source (Supplementary Fig. 3).
Because our model is constrained only by the fluctuating levels of replication factors, it provides a unique understanding of the kinetics governing the reactions between them.
Because our regeneration model only accounted for regeneration in the first year after fire, we also developed two alternate scenarios that allow for regeneration throughout the modeling period beginning 20 years after fire (see Additional file 2).
Because our model takes into account only whether a child is living anywhere in a fixed distance (500 m, 1,000 m, or 1,500 m) radius of an airport, children who live very close to or downwind from a runway could be affected more significantly than the average value that we estimate for all children living within the buffer.
This is the case because our model deals with random spatial translations only.
However, it should be stressed that for our model a quantitative analysis of the scanning behavior is irrelevant because the model only incorporates our observations that (even blind) males never scan in daylight, while they always scan in the dark, independent of their genotype with the exception of Poxn-pRes; Or83b2 males that virtually do not court in the dark (Figure 3C).
Pyron et al. objected to our model because only two climate axes were included (actually, we used four, mean monthly precipitation and temperature, plus duration of hibernation and duration of aestivation, none of which Pyron et al. considered).
