Sentence examples for because of variants in from inspiring English sources

This leads to the hypothesis that some people with reduced ability to respond might be more susceptible because of variants in these generic stress response genes".

Because the majority of variants in the gold standard are heterozygous (the ratio of heterozygous to homozygous alternative variants is 5 to 1), the main allele fractions we evaluated are 4%, 8 %, 18, and 50%.

Coding regions are targeted because the functional consequences of variants in these regions are much better understood than those in noncoding parts of the genome.

This is because studies in populations of variants in genes encoding a drug target protein can be considered to be a type of natural randomised trial and could be used to help predict the on-target effect of modifying the same target pharmacologically.

Because we detected such a large group of variants in one single gene, a detailed examination of the different parameters that play a role in alternative splice regulation could be performed and compared statistically.

clinical interpretation of variants in cancer.

Our hypothesis is that outlier samples have gene expression values that were generated by a different mechanism than the rest of samples because of genomic variants in the pathway's genes or in their regulators.

Failure to find a causative variant occurs if there is technical failure, or if no causative variant is present in these genes (because of causative variants in other (un known genes or because the patient does not have OI).

He spoke of variant in genes in cases of incest.

Allelic heterogeneity across different ethnic groups in single-marker analyses is expected in complex diseases because of the occurrence of pathogenic mutations across multiple domains of disease genes (allelic heterogeneity) or because of the absence of these variants in some data sets or ethnic groups (locus heterogeneity).

Because the role of mtDNA variants in most of these phenotypes is still a matter of debate, it is fundamental that either novel or previously reported mtDNA variants of interest are highlighted and brought forward to subsequent analyses, since functional studies aimed at ascertaining the potential pathogenicity often require cumbersome efforts.