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But oral administration is rarely used because of toxic effects on the liver.
Biological oxidation of chlorophenol compounds is difficult because of toxic effects of those compounds on microorganisms.
We utilize biotin-independent E. coli for the production of the high-value protein streptavidin which was hitherto restricted because of toxic effects due to biotin depletion.
Roughly three-fifths of drugs in clinical development falter because of toxic effects, other safety issues or their failure to do what they are supposed to.In the clinic, companies are trying a variety of tools—such as web-based patient recruitment and data management to cut time and money from the process.
No patients required permanent discontinuation of zidovudine because of toxic effects.
However, an increase in ROS beyond a certain level will harm HSCs because of toxic effects.
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Because of the rapid onset of toxic effects from cyanide poisoning and the difficulty in developing a rapid and sensitive analysis for ATCA, the most appropriate target for diagnosis of acute cyanide exposure is the direct analysis of cyanide as soon after exposure as possible.
In a study on primary hippocampal cultured cells, A β25 35 was used to establish A β-induced neuronal cell death, because of its similar mechanism of toxic effect.
The explanation for this "muscle paradox" is that skeletal muscle is affected not because of TP dysfunction (or lack thereof), but rather because of the toxic effects of accumulated dThd and dUrd (Hirano et al, 2006).
However, the extraneously introduced metabolic pathway converting NAD(P)+ to NAD(P H could decrease the NAD(P +/NAD(P H ratio, especially in the late stages of 3-HP production, because of the toxic effects of 3-HPA and 3-HP on cellular physiology1.
For many years concerns have been expressed about the extent of fatal poisoning with the analgesic co-proxamol (dextropropoxyphene in combination with paracetamol), especially its use for suicide. 1 2 Death occurs largely because of the toxic effects of high levels of dextropropoxyphene on respiration and cardiac conduction.
More suggestions(15)
because of peer effects
because of toxic emissions
because of late effects
because of special effects
because of adverse effects
because of toxic additives
because of toxic fandoms
because of toxic politics
because of several effects
because of environmental effects
because of toxic fans
because of toxic events
because of toxic leaks
because of masking effects
because of confounding effects
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