Despite the large range of available pharmacological treatments, they remain unsatisfactory because of their delayed onset of action (3 6 weeks) and their partial therapeutic efficacy.
However, these markers remain unsatisfactory because of their low sensitivity and/or specificity or because of their limited applicability, for example, telomerase in breast lesions (Clark et al, 1997) or ret/PTC rearrangements in thyroid cancer (Cheung et al, 2001).
Weed performed numerous pilot experiments in his effort to identify a dye solution that was best suited for his studies: "Many solutions were tried, but all proved unsatisfactory because of their toxicity or their diffuse tissue staining" [ 36].
There is a large collection of synthetic as well as natural product derived drugs available for the treatment of various ailments, but the treatment is often unsatisfactory because of their severe side effects and drug resistance.
Because of the unsatisfactory legal system, commercial disputes with other companies are best avoided.
Mr. Skell, 42, said he was fired a few months later because of an unsatisfactory performance rating, which he disputes.
If the attempt is in any way unsatisfactory, it is probably because of something unsatisfactory in the subject's own character; Hawthorne withdraws from the biographer as successfully as he did from his family and friends.
The Polska Telefonia Cyfrowa unit of Elektrim, Eastern Europe's largest mobile phone company, said it had fired its chief financial officer, Stanislaw Majewski, because of his unsatisfactory performance.
For other critics the whole of Aristotle's canon stood condemned because of his unsatisfactory account of local movement and the consequences it had in the areas of mechanics, dynamics, cosmology, and astronomy.
The special measure is being introduced because of the unsatisfactory state of anti-doping bodies in the two countries, which the IOC president, Thomas Bach, said put "very serious doubts on the presumption of innocence".
