The agreement between Bovis and the office of the Manhattan district attorney, Robert M. Morgenthau, has been under consideration partly because of some of the significant problems an indictment against the company would raise, a law enforcement official said.
These findings should not encourage people to start drinking alcohol for its health benefits, because of the significant health problems associated with heavier use, as described below.
They immediately ran into the significant problem of trust.
"I took emergency action to ensure seniors and disabled Californians get lifesaving medications they are in danger of losing because of significant problems with the new federal Medicare prescription drug program," Mr. Schwarzenegger said.
Basically, I'm excited for FFXV, and while it just recently saw its release date slip from late September to the end of November 20166), my preview with it leaves me unconcerned that this is because of any significant problems with its production.
As shown in Table 1, one such combination [pramlintide plus metreleptin (Ravussin et al., 2009)] entered Phase II clinical trials but the programme was stopped because of significant problems with antibody generation and skin reactions (http://www.takeda.com/press/article_42791.html).
The report also highlighted increasing spending by boards on costly agency workers because of significant problems with recruitment and retention of staff, as well as a lack of workforce planning for new models of care to deliver more community-based services.
According to the authors, "the studies provide some evidence of associations with a range of serious and common health problems," although they also noted that the studies they reviewed have limited validity and precision because of significant problems with systematic and random errors.
The reason they are drinking so much alcohol is because of other, hugely significant, problems in their lives: poverty, mental illness, housing difficulties, domestic violence, loneliness.
The S.E.C. began investigating Longtop Financial Technologies of China for accounting fraud earlier this year after Deloitte's Chinese affiliate resigned as its auditor because of significant problems in verifying its financial statement.
