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Because of the interim analysis, the primary analysis of the study was performed at a significance level of 0.0467.
Only five papers (16%) reported that the final results were adjusted because of the interim analysis, e.g. by using an alpha spending approach, four (13%) of which reported all interim analysis parameters presented in Table 6.
Consider the uncomfortable position of having to explain to a colleague why his small p-value calculated at the end of a clinical trial that had included an interim analysis with a group sequential stopping rule (that had not been met) could not be considered as "statistically significant" because of the interim analysis that was carried out a year ago on the first half of the data.
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Because the alpha level of the interim analysis is set to α = 0.001, the sample size calculated from a group sequential approach will be similar to the sample size of the fixed study approach.
In the news conference, Mr. Sharon, who was brought into the Government partly to placate the right, presented the Israeli withdrawal from the West Bank as an inevitability because of the Oslo interim peace agreement signed by the previous government in Oslo.
General Ammar was trying to placate protesters who are demanding the dissolution of the interim government because of the continued dominance of officials from Mr. Ben Ali's old ruling party.
But what of the interim government?
Therefore, this manuscript presents the results of the interim analysis.
In early 2007 the interim Sports Minister Lekh Ram Vayeshnoi appointed Serevi to the board of the interim Fiji Sports Council.
16 months from the signing of the interim agreement.
In retrospect, that looks like a policy of malign neglect, because in the interim, the conflict ground away trust and good will between not only Israeli and Palestinian leaders but also between their people.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com