Getting on an airplane was out of the question because of the dose of radiation she would give other passengers.
Patients with more frequent cluster attacks per day are unable to use triptans because of the dose limit they can use in a 24 h period.
Because of the dose limit for critical structures such as brainstem and spinal cord, administering a dose of 60 Gy to patients with recurrent head and neck cancer is challenging for those who received a previous dose of 60−70 Gy.
The trial could not be blind for peptide dose because of the dose-escalating design.
Because of the dose-escalating design, the trial could not be blinded for dose.
Because of the dose- and strain-dependent effects of P. fluorescens on D. melanogaster survival and development, the population sizes of the three strains were assessed from surface-sterilized larvae (Fig. 7).
Analysis of data from two IPTc studies conducted in Senegal showed that the incidence of vomiting was most marked in children who were overdosed, because of the dose stratification used, and that it should be possible to reduce the occurrence of vomiting by adjusting the dose [34].
It is speculated that this may be because of the dose intensity achieved in this arm of the study.
It is difficult to escalate the dose of RT for certain patients because of the dose limitation of organs at risk.
Increasing the dose of the synthetic dsRNA to improve its anti-tumor activity is not feasible because of the dose-dependent severe adverse effects [ 15, 18].
