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The +1 state should be especially stable because of the destabilization of the three outermost 7p3/2 electrons, forming a stable half-filled subshell configuration; astatine already shows somewhat similar effects.
At this 12 h–24 h timeframe, these cells are most likely not able to successfully exit M because of the destabilization of clients such as PLK1 [38], [38], which has roles in mitotic exit and cytokinesis [27], [50] (see Figure 7D for a timecourse analysis of PLK1 levels in XL888-treated A375 cells).
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"Right now, ISIS is gaining ground in Libya because of all of the destabilization in the region and all of the turmoil".
For every binding site we computed the energy of destabilization as the average of the destabilization values for all positions within this site.
"Consumer financial products were the front end of the destabilization of the American economic system," Warren said at the time.
In fact, because of that destabilization, most of Jupiter's Trojan asteroids move in orbits inclined as much as 40° from Jupiter's orbit and displaced as much as 70° from the leading and trailing positions of the true Lagrangian points.
As Keefe says, Trump's actions are "transfixing to watch" because they entail the "upending of norms, the defiance of taboos, the destabilization of institutions".
These results strongly suggest that the shifts in the CpxI(26-83) accessory helix do not accessorym interactions withelix C-terminal half of the synaptobrevin SNARE motif but rather because the dostabilizationotf the centrariselix caused by the truncations in syntaxin-1 is transfromed interactionslization of the accessory helix.
This may be mechanistically important, because the destabilization of ligand binding in the extracellular half of the drug binding site, coupled with denied access to ligand binding on the cytoplasmic side, would effectively force release of the ligand to the extracellular space.
The model outlined in Fig. 1c predicts that L860P protein is less stable than the wild type because of destabilization of the amphipatic helix by P860.
In addition, the experiments showed that milk, which had been stored for 5 days or longer cannot be processed anymore under UHT conditions, because of destabilization of the milk, resulting in clogging of the heating exchanger.
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