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Because of the complex interactions and the many degrees of freedom, the calibration task itself has become a main bottleneck.
Pattern formation in ternary eutectic microstructures is difficult to predict because of the complex interactions between diffusion and surface energies, as well as the large number of possible configurations which three phases can assume.
Given that precise forecasts of regional hazards are challenging, because of the complex interactions between processes on many scales, a range of probable geomorphic change in response to storm conditions is often more helpful than deterministic predictions.
Simulation of photonic systems are a necessity because of the complex interactions within and between components, and the need for rapid design cycles using the latest technologies for meeting the growth in bandwidth demand.
However, the interpretation of such measurements can be misleading because of the complex interactions between the target materials (e.g., suspensions of highly reactive and variably aggregated nanoparticles) and aquifer materials (sediments and groundwater), and multiple complications related to sampling and detection methods.
Preferential shell-loading yields the highest catalytic effectiveness but because of the complex interactions between the reaction kinetics and the activity profiles within the pellets, there is no simple relationship between diffusion lengths and effectiveness even for large values of the Thiele modulus.
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As reviewed by Fessler [ 41], these factors are difficult to tease apart because of the complex interaction between cardiac and lung volume and the complexity of the in series interactions of the lung and pericardial constraint.
The study of local hydrodynamic properties of three-phase bioreactors in biotechnology processes is of great importance, mainly because of the complex interaction between bioreactor and microorganisms.
The local urban microclimate is difficult to predict because of the complex interaction of physical phenomena across a large range of time and length scales.
Water sprinkler systems are usually used to extinguish underground conveyor belt fires, but because of the complex interaction between conveyor belt fires and mine ventilation airflow, more effective engineering designs are needed for the installation of water sprinkler systems.
The groundwater flow system at the site exhibits a multi-scale pattern that is difficult to simulate using standard modeling tools because of the complex interaction between ambient hydrologic stresses and on-site remediation operations.
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