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Ab B-R3 targets D2 of gp130 and does not detect CAgp130 probably because of the activating deletion located within this domain.
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Because this makes isolation and identification of the activating 5'-tagged region(s) laborious and time consuming, single T-DNA copy integrations are usually preferentially analyzed [ 35- 38].
But in vitro IFN-γ stimulation seemed to have little effect on peripheral monocytes from RA patients, possibly because of the already activated condition of RA monocytes in vivo.
Because of the ability of Activated Protein C to limit thrombin generation, it can also reduce the activation of a precarboxypeptidase B commonly referred to as thrombin activatable fibrinolysis inhibitor [ 14, 15].
Roughly 50% of all cancers have an activated Ras signalling pathway because of activating mutations in the ras gene itself, and of genes for proteins that act up- or downstream of ras.
The irradiated areas were intentionally kept small because of the potential hazard of activating systemic disease by irradiating large skin areas in patients with SLE.
The initiation and/or progression of these tumors may very well be because of activating mutations in the PTPN11 gene.
Because of the overlapping fluorescence between the activated aldefluor substrate and GFP expression by flow cytometry, oncolytic HSV1-hGM-CSF was used instead.
Farley nodded approvingly, and said, "You reconsider the art work because of the way it is activated by the performers".
Because of the anionic phospholipid exposure, activated platelets and platelet-derived microparticles serve as platforms to promote systemic coagulation and thrombosis (Warren and Vales, 1972).
34 It is likely that the prothrombotic effect of FEIBA is greater than that of PCCs because of the coagulation factors being activated and that, if used, much smaller doses will be required than those used for treating patients with haemophilia.
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