Sentence examples for because of substantial toxicities from inspiring English sources
Its clinical application remains limited mainly to the treatment of life-threatening diseases because of substantial toxicities associated with currently available BMT regimens.
The other study was terminated because of substantial toxicity (Li et al, 2009; Patel et al, 2009).
The natural enediynes have seen limited use as clinical drugs mainly because of substantial toxicity, however, various polymer-based delivery systems or antibody drug conjugates (ADCs) have shown great clinical success or promise in anticancer therapy.
"There is risk of substantial toxicity, and it doesn't work on everybody.
Methotrexate appears to be a viable alternative immunosuppressive agent whereas cyclophosphamide treatment should be carefully considered because of substantial risk of toxicity.
This is because RCT carries substantial toxicity, and because preoperative chemotherapy alone, without radiotherapy, is a valid curative alternative to RCT[ 28, 29].
Because of substantial PCB contribution to dioxin toxic equivalents, total dioxinlike toxicity can only be determined if dioxins, dibenzofurans, and dioxinlike PCBs are measured.
These combination treatments are associated with substantial toxicities and a median duration of responses in the order of months.
Results: In contrast to other [18F]fluoroethylation reactions, RCY was low (<5%) because of substantial defluorination.
However, it is clear that still too many patients receive this therapy with little likelihood of benefit and substantial toxicity.
