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Methotrexate appears to be a viable alternative immunosuppressive agent whereas cyclophosphamide treatment should be carefully considered because of substantial risk of toxicity.
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Awareness of this coexisting anomaly is important for pancreatic resection because of the substantial risk of pancreatic fistula [3].
Although patients with UC usually undergo periodic OC, because of the substantial risk of CRC, WE-MDCT studies in UC patients should be carefully scrutinised to identify features that suggest an underlying malignancy, particularly in patients with failed endoscopic surveillance or incomplete endoscopy.
The motion further contends that this irrelevant statement should be withheld from public dissemination because of the substantial risk that public disclosure will lead to widespread hostile publicity which would substantially impair the Defendant's fair trial rights, and would pose a serious threat to the administration of justice.
It clearly makes no sense to assign a p53 status to samples containing only very small numbers of tumour cells, because of the very substantial risk that the result reflects only the status of the normal cells in the biopsy.
However, because of substantial heterogeneity of risk estimates across propensity score strata (likely because the propensity score was highly discriminative (that is, a high C statistic) given substantial differences in characteristics between TNF-α inhibitor users and non-users), which violates the basic assumptions of this approach, it was abandoned.
However, this approach is not recommended in the neurointensive patient because it involves a substantial risk of worsening the hypovolaemia [ 74].
However, bearing in mind the volatility of the Gaddafi regime, the gift involved a substantial risk because of the length of the relationship".
In January, a federal magistrate judge in Ohio blocked the state from using a new three-drug combination for lethal injection, because he determined that the use of midazolam created a "substantial risk of harm".
To solve the problem, we studied plasma treatments on the polymer surface because there would not be a substantial risk of damaging the bulk properties of the polymer and the stent by plasma surface treatments.
My company, Audit Integrity, is in the business of uncovering such wrongdoing because it represents a substantial risk to stakeholders.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com