Sentence examples for because of suboptimal concentrations from inspiring English sources
Colistin was less effective in patients with osteomyelitis, biliary tract disease, endocarditis, and suppurative infections of the lung (probably because of suboptimal concentrations locally), and it was ineffective in the treatment of Gram-negative infections in neutropenic patients [ 10, 11, 13].
JTA009 co-stimulated peripheral blood T cells in the presence of suboptimal concentrations of anti-CD3 mAb.
To test this hypothesis, we generated an experimental system where FFAs were exogenously supplied, and the effect of suboptimal concentrations of norepinephrine (NE) on energy expenditure was tested.
Exposing HMC-1 cells (a human mast cell line) to a combination of suboptimal concentrations of E2 and an environmental estrogen had an additive effect on degranulation.
Concomitant application of suboptimal concentrations of LY294002 and sunitinib significantly suppressed vegfaa expression and fully inhibited hypervascularization in ptena −/−ptenb −/− mutant embryos (Fig. 5A,I).
Autologous NK cells were sorted and either kept unstimulated in the presence of suboptimal concentration of IL-2, or activated by a combination of PHA and IL-2.
We found reasonably high CSF concentrations of nelfinavir, but suboptimal concentrations of saquinavir.
Inadequate drug penetration into the CNS is of concern firstly as the CNS may form a drug sanctuary for HIV, and secondly because the suboptimal concentration of drugs in this compartment favors the emergence of drug resistance.
180 Distinct resistance patterns are likely to arise from the compartmentalization of viral replication and suboptimal concentrations of drugs in semen.
Analysis of pAkt levels following treatment with suboptimal concentrations of LY294002 or sunitinib indicated that these treatments did not fully suppress enhanced pAkt levels in ptena −/−ptenb −/− mutants.
However, in our experience previously published immunoassay methods are not replicable without detailed knowledge of EIA procedures, contain errors, or report suboptimal concentrations of reagents.
