eWeighted average, because model assumes equal mortality due to lack of significant mortality difference (linezolid = 63 of 224; vancomycin = 59 of 224).
On July 19 , 2004 the independent Data Safety Monitoring Committee recommended early termination of the trial because of a significant mortality benefit in the cohort receiving fixed-dose ISDN-HYD.
The epidemiology and outcome of acute kidney injury (AKI) continues to be a subject of much interest, not least because of the significant mortality, morbidity and costs associated with it.
Among these syndromes, MRSA bloodstream infection (BSI) is of special concern because of the association with significant mortality and morbidity [ 5- 7].
All in all, the results of the second series show again that harnessed bees drink deterrent substances such as LiCl, quinine, amygdalin and L-canavanine and that ingestion of quinine, LiCl, and amygdalin yields significant mortality, probably because of a toxic, post-ingestional effect of these substances.
The CQC inspected the unit over two days in December because it "had been identified as a significant mortality outlier when compared to similar services".
The doses of KA and pilocarpine were chosen because they elicited the most severe seizures without significant mortality.
There were, however, six clinical trials terminated early because of significant drug toxicity, as well as two trials where the mortality was higher in the treatment group.
This approach results in significant mortality, morbidity and unsustainable expense.
Fractures related to osteoporosis are widely recognized as an important health problem because of their significant morbidity, mortality, and costs.
