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Finally, variants segregating on any of the edges of the square can also become fixed because of random drift.
Such regions may also occur within the genome because of random drift and are not distinguishable from regions that have undergone a selective sweep.
And define V x) as the probability that x changes because of random drift, either decreasing by amount δx with the probability V x)/2 or increasing by the amount δx with the probability V x)/2.
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To understand the nature of random drift, consider a simple example.
In just the same way, the larger the population, the less important the effect of random drift on gene frequencies; in the infinite limit, drift has no effect.
One important effect of random drift is to decrease the degree of heterozygosity in a population over time.
Wright wrote that the "restriction of "random drift" or even "drift" to only one component, the effects of accidents of sampling, tends to lead to confusion".
Many of these changes were introduced as a result of random drift.
Population differentiation may arise because of random genetic drift and FST may be influenced by unequal sample sizes.
Loss of alleles and reduction in genetic variation can also occur during the early stages of establishment because of random genetic drift due to small population size and selective pressure exerted by novel environments [16], [24].
Recent miRNA haplotypes derived directly or indirectly from original haplotypes that maybe the most ancestral haplotypes or the lost haplotypes because of random genetic drift and evolutionary fluctuation at DNA level, which would adapt to the specialized miRNA biogenesis machinery [34] and co-evolve with the complex regulatory networks toward a strong evolutionary pressure.
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