Increased work of breathing might be a problem in children when BIPAP is used in the weaning phase because of a prolongation of periods of low pressure levels.
Because of this prolongation in survival, GC patients live longer, but have a greater possibility of developing multiple primary cancer (MPC).
The degree of "prolongation" was not predefined however because of the high clinical variability and left up to the treating physician.
Patients receiving rivaroxaban may have mild to moderate prolongation of clotting time tests beyond reference range, however the degree of prolongation is variable among patients.
The first sign of prolongation and calculated extension of vision beyond the garden proper appeared in the grounds of Dampierre.
Assessment of the QT interval is of clinical importance because prolongation of repolarization is often associated with conditions such as electrical instability and sudden cardiac death (Algra et al., 1991), but can also be indicative of the pro-arrhythmic activity for new chemical entities (De Clerck et al., 2002).
Because the prolongation of deposition time caused the interlocking of the deposited Ag owing to the excessive deposition of Ag nanoparticles, the period of electroless metal deposition was standardized to 15 s.
Because prolongation of the half-life of most of the mutated p53 protein induces its nuclear accumulation, it is generally believed that the p53 pathway does not fully function in tumors with high p53 nuclear immunoreactivity [ 31- 33].
This interpretation is seen as conservative, because a prolongation of the time horizon from 3 years to the whole lifetime of the patients might well improve the cost-effectiveness of MARS by decreasing the costs per life year gained.
However, we also showed that the development of OB per se did not have an additional prognostic impact on either PFS or OS because no prolongation of PFS or OS was observed in the patients who achieved better than VGPR according to the development of OB.
Also, patients may terminate the treatment because of side effects, prolongation of therapy, or relief of the symptoms [4].
