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However, the consideration of admission to an intensive care unit (ICU) is a particular clinical and ethical challenge because of poor outcome [ 28- 32].
For high-level peripheral nerve injury, because of poor outcome due to the long duration of nerve recovery at a low level distally, we recommend using side-to-side neurorrhaphy.
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Because some individuals may drop out early because of poor outcomes, we will also investigate missing not at random models based on informative dropout models.
As mentioned previously, discontinuation of therapy is the least favorable option because of poor outcomes associated with therapy interruption or termination.
Re-transplantation for graft failure due to recurrent hepatitis C is controversial, and some centers abandoned the procedure because of poor outcomes [ 1, 4, 5].
This may have been partly because of poor outcomes from treatment of symptomatic breast cancers and the evidence-based promise of a 30%% reduction in population breast cancer mortality.
The emergence of plasma creatinine in the predictive model is not surprising because renal impairment is a predictor of poor outcome in non-paced patients with heart failure.
miR-206 levels in fusion gene-negative RMS may have clinical implications because ERMS currently lack molecular markers indicative of poor outcome and such patients could benefit from treatment intensification.
NSE threshold for prediction of poor outcome appear controversial, in part, because of variability in dosage timing and measurement techniques.
We confirmed that BNP or proBNP levels identified patients at higher risk of poor outcomes, but because they had a low specificity and consequently low PPV, their clinical use to identify those at risk of mortality in this population may be limited.
However, conclusions about long-term efficacy must be tentative, because a possible bias to under reporting of poor outcomes cannot be excluded, without complete follow-up data.
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