Sentence examples for because of point mutations from inspiring English sources

However these studies do show that there are differences between species as the repeat expansions have different critical lengths in mouse and humans, and the rates of perfect repeat loss because of point mutations also varies significantly between species, so that in some species repeat shortening and loss is more frequent than expansion [12], [16].

Single-nucleotide polymorphisms arise because of point mutations that are selectively maintained in populations.

Some isolates possess additional plasmid-mediated resistance to trimethoprim and low-level resistance to ciprofloxacin because of point mutations in the gyrA gene (1).

On the molecular level, the accumulation of multiple mtDNA deletions in muscles is characteristic of CPEO, which is distinct from other inherited mitochondrial diseases because of point mutations or copy number reduction of mtDNA in affected tissues.

Up to now, all FQ-resistant GBS strains described were highly resistant because of point mutations in gyrA and parC QRDR; a parC mutation at position 79 was present in all strains.

During the 1990s, this clone acquired a large conjugative incHI1 plasmidasmid encoding resistance to ampicillin, chloramphenicol, and co-trimoxazole (4, 5 ); also in the 1990s, this MDR clone became resistant to quinolones and showed decreased susceptibility to ciprofloxacin because of point mutations in the chromosomal gyrA gene (2 ).

A consensus sequence could be unambiguously determined because the number of point mutations in the clones was low, and never more than 1 of the 5 clones showed a difference from the consensus sequence (data not shown).

We considered that the number of base substitutions were the same as that of point mutations because no complicated mutations were found at a given substituted site.

Tandem hybridization uses shorter capture probes than traditional oligonucleotide array hybridization, which may contribute to increased discrimination of point mutations because the single base mismatch acts on a less stable duplex formed between the target DNA and the shorter probe.

This is advantageous because it can reveal a series of point mutations in the coding sequence of a candidate gene that give a variety of allele types, including nulls, hypomorphs, hypermorphs and dominant-negative alleles.

There are two types of point mutations: transition mutations and transversion mutations.