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It is therefore likely that such regimens were more frequently changed because of patient request and in order to avoid compromising adherence and therapeutic effectiveness.
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We used a previously described taxonomy of patient requests to categorize all patient requests contained in the messages.
We used an indirect means of measuring change, because we recorded the number of GPs' prescriptions presented to pharmacies by patients in both groups, rather than the number of patient requests.
In practice, physicians are reluctant to forego adequate verbal communication with the patient because they wish to verify the voluntariness of patients' request and the unbearableness of suffering.
In the overall population, 86% of patients switched from their previous therapy to everolimus because of progression, and 14% switched because of other reasons (e.g., intolerance or patient request).> -wrap-foot>> -wrAbbreviationseviations: MSKCC, Memorial Sloan-Kettering Cancer Center; KPS, Karnofsky performance status.
This was mostly because of moderate neutropenia, but occasionally on patient request.
Some hospitals may be reluctant to offer this without your requesting it because of patient privacy rights.
All 26 patients discontinued treatment with motesanib because of the following reasons: disease progression (n=14), withdrawal of consent (n=5), administrative decision (n=3), adverse event (n=2), death (n=1), and patient request (n=1).
Twelve (5%) and 34 (14%) patients discontinued treatment because of disease progression or death in the bosutinib and imatinib arms; 80 (32%) and 38 (15%) discontinued for other reasons (adverse events, patient request, investigator request, protocol violation, failure to return, lost to follow-up and other).
14 patients withdrew because of the patient's request or other reasons.
The relatives of the other patient requested that he remain anonymous.
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