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Tumours may be missed because of observer error, dense breast tissue or even poor technique.
The authors do not recommend the use of anti-MGMT immunohistochemistry as a routine biomarker for diagnostic purposes because of observer variability and lack of association with the MGMT promoter methylation status and survival.
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Because of observers' potential prior expectations that Waldo is always present in a "Where's Waldo?" search, they received both written and verbal instructions that Waldo was not always present, and they were to make a button response to indicate Waldo was either present or absent from the display.
To prevent the occurrence of systematic differences between observers because of repeated testing, the test sequence, and thus observer order, was randomized.
Gordon Ramsay, said: "Winning The Observer Food Monthly award for Best TV Show meant a huge amount to everyone involved in the making of the series because the readers of Observer Food Monthly have to be the most discerning and food-savvy critics of all".
It occurs because of a combination of observer bias (when observers disagree on the frequency of the occurrence of a condition) and prevalence bias (when the frequency of the occurrence of a condition is either very low or very high).
By covering technology and the bumpy road of innovation, we're covering ourselves, and, because of the observer effect, that impacts both ourselves and the process.
Because of this, Observer September (Michael Cerveris) says Peter never existed.
There was a risk of observer bias because the open-label study did not have any placebo group.
Different observers may get different results, but previous studies on observer variation have not been informative, because of few observers, few trials, or few data.
The question of comparison is keen at the moment, because the majority of observers and musicians who have commented on the "new" Carnegie acoustics since last year's extensive renovations have found them altered.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com