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However, multivariate genetic analyses of data from natural populations are challenging because of modest sample sizes, incomplete pedigrees, and missing data.
Another study, where mean DDE levels were lower (212 ng/g lipid) than in our population, reported a weak positive association between prenatal DDE concentrations and BMI in the first 3 years of life (Verhulst et al. 2009); sex differences were not reported because of modest sample size (n = 138).
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A number of the population clusters in the ASD study are of modest sample size (n < 100) and five population clusters could not be included because of insufficient sample numbers.
Because of a modest sample size used, our analysis will focus on a three-SNP analysis, although the model can deal with any number of SNPs.
The correlations that we found may be unstable because of the modest sample.
Insufficient statistical power because of the modest sample size (N = 18) may have played a role in limiting the significance of the statistical comparisons conducted (Additional file 3).
The fact that we did not observe a general difference in SCPs between high impulsives and low impulsives may therefore be attributable to limited statistical power because of the modest sample size (N = 18).
Though it is easy to regard TCF7L2 as having a 'large' effect because of its detectability in quite modest sample sizes, this does not translate into immediate clinical utility.
We could not assess gender differences in more severe forms of IPV because of their low prevalence and our modest sample size.
This was an exploratory study with a modest sample of MDs.
Third, with a modest sample size of 116 participants, power would not be large.
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