Because of missing samples, cytokines were obtained only in a subgroup of 108 participants.
Because of missing sample collection, some early pregnancy losses might not have been identified.
We excluded 25 patients because of missing samples, and 2 patients were excluded because of unknown outcomes and/or missing patient data.
Because of missing samples for subjects 5, 11, and 12, it was not possible to define the elimination-phase parameters for these subjects, and the area under the dexmedetomidine concentration-time curve extrapolated to infinity (AUC0-∞) was estimated by using the mean elimination half-life of the other patients.
Other limitations included the study size because of numbers of patients recruited, missing samples when patients could not be located, the lack of pyrazinamide susceptibility testing, and some uninterpretable contaminated cultures.
Because of the missed samples and the small number of subjects completing the blood sampling procedures, it was not possible to analyze the parameters of pulsatile LH secretion.
We enrolled 485 patients; of these, we excluded 116 cases because of known immune deficiency and 19 cases because of missing plasma samples, leaving 350 subjects for analysis.
Participants excluded from analysis because of missing urine sample (n = 1,064) had similar sociodemographic characteristics as the analyzed cohort (data not shown).
Of the initial study group of 313 men, 5 were excluded: 1 because of abuse of anabolic steroids, 2 because of missing blood samples, and 2 because of missing questionnaire information, leaving 308 men eligible for analyses.
