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*Ct, cycle threshold; ND, not done because of missing samples.
Because of missing samples, cytokines were obtained only in a subgroup of 108 participants.
An additional three patients were excluded because of missing samples at early or intermediate time points.
We excluded 25 patients because of missing samples, and 2 patients were excluded because of unknown outcomes and/or missing patient data.
Because of missing samples for subjects 5, 11, and 12, it was not possible to define the elimination-phase parameters for these subjects, and the area under the dexmedetomidine concentration-time curve extrapolated to infinity (AUC0-∞) was estimated by using the mean elimination half-life of the other patients.
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Because of missing sample collection, some early pregnancy losses might not have been identified.
Other limitations included the study size because of numbers of patients recruited, missing samples when patients could not be located, the lack of pyrazinamide susceptibility testing, and some uninterpretable contaminated cultures.
Because of the missed samples and the small number of subjects completing the blood sampling procedures, it was not possible to analyze the parameters of pulsatile LH secretion.
In several cases we were not able to analyse the receptor status in our laboratory because of long preservation time or missing samples.
Missing samples occurred because of death, discharge from hospitals and samples not drawn.
Four of these patients were later not included in the analysis because of incomplete registration forms (3 infants) or missing samples for blood culture or PCR (1 infant).
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