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AQP4-IgM was elevated in AQP4-IgG positive patients, however because of lower sensitivity and specificity its role as biomarker in NMO remains unclear.
Dispersal estimates (Nm) using the private allele method [68], implemented in GENEPOP 4.0 [69], is potentially less biased than the Fst island model method when using highly polymorphic markers such as microsatellites because of lower sensitivity to homoplasy [70].
Surface autocorrelation functions were only tested in the first two models (428 and 416 descriptors) because of lower sensitivity scores.
SPIDER greatly reduced the initial number of articles identified on a given search due to increased specificity, however because of lower sensitivity omitted many relevant papers.
The often-negative association of the weighting factor with the lnDOR gives studies with lower discriminative diagnostic odds ratios – because of lower sensitivity and/or specificity – a larger weight.
In ROI contrasts of CN− vs CN+ groups, lower ROI average thicknesses were observed in the CN+ group but the differences did not reach statistical significance possibly because of lower sensitivity (Supporting Information Fig S2).
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Ultrasonography was found to be more convenient but was of lower sensitivity, because lung lesions covered by aerated lung tissue were undetectable [ 7- 9].
In contrast, MRI was unable to demonstrate targeted cardiac localization of MSCs in part because of the lower sensitivity of MRI.Noninvasive radionuclide imaging is well suited to dynamically track the biodistribution and trafficking of mesenchymal stem cells to both target and nontarget organs.
They argued that the estimated mortality reduction from screening may be lower than the mortality reduction predicted by MISCAN (van den Akker-van Marle et al, 1999) because of the lower sensitivity of the UK screening programme in the early years of screening.
Although Sypro Ruby staining of the gels was not particularly helpful for detection of peptides (probably because of its lower sensitivity), Cy3 labeling of peptides proved to be powerful.
Because of the lower sensitivity of oral fluid WBs, confirmatory testing following a reactive rapid test should be conducted using serum or plasma, when possible.
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