Thus, for microsatellites, because of lower frequencies of the most frequent allele and higher levels of genetic diversity, the maximum value of F is substantially more constrained than the corresponding maximum of F for SNPs.
Socioeconomic status is known to be an intervening factor, mostly because of lower frequencies of patients undergoing interval screening, treatment's delay and smaller availability of modalities of treatment, such as chemo, hormone, and radiotherapy, among the less affluent populations [ 6- 9].
Because of the generation of lower frequency alleles, larger sample sizes are needed to take advantage of the additional information present in haplotypes.
Resistance to carbapenems might have been underreported at the beginning of our study period because of a lower frequency of susceptibility testing of these agents and the inability of antimicrobial susceptibility test methods to detect low-level carbapenem resistance.
Because of the lower frequency of inhibitor development, there is less experience in the management of inhibitor in patients with haemophilia B. ITI can be attempted in these patients, but the risk of complications is higher than in haemophilia A (Benson et al, 2012; DiMichele et al, 2007).
In Bordils, this correlation is not significant because of the lower frequency of this arrangement in this population.
Due to the recessive nature of null alleles, these secondary species appear artificially closer to their C. reticulata parent because of the lower frequency of null alleles in this gene-pool compared with the other ancestral species.
Associated diseases were less frequent in the once-daily detemir group (54 vs. 64%, P < 0.05) because of a lower frequency of treated hypothyroidism (2.4 vs. 5.4%, P < 0.05).
However, the Institute considered that the cost-effectiveness of insulin glargine was less well established for people with type 2 diabetes, principally because of the lower frequency of hypoglycaemic episodes among this group and consequently the relatively limited scope for improvement.
The reason for the high ignition energy needed to initiate disproportionation of trifluoroethylene was considered to be that the flame kernel needed to have a large size and a long lifetime to propagate the disproportionation reaction because of its lower frequency factor of producing solid graphite.
