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HMGA2 and Lin28B proteins are highly expressed in embryonic tissues, downregulated in differentiated tissues and, because of low expression of let-7, re-expressed in tumors, where their levels positively correlate with tumor progression.
Because of low expression of Spink9 mRNA in most tissues and cells, all PCR products above were then diluted 20-fold in water and used for nested PCR and real-time PCR.
[16], [28], [33], [34] Secondly, the reason for only some of the tumor cells being positive for EBV expression could be because of low expression of protein in tumor cells or because of poor accessibility of the antibody to the antigenic site.
Unfortunately, we could not detect the localization at earlier stages because of low expression levels of the fusion protein.
Following data filtering, 47,591 features were discarded from an original 64,896 because of low expression.
The remaining 152 miRNAs, mostly soybean specific, were not detected, possibly because of low expression levels or spatial expression pattern.
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This may be because the problem of low expression, as seen with other transcription factor genes, is further exacerbated by expression being restricted to just a few small cells.
In RNA analysis, a targeted approach can provide more evidence of low expression transcripts, because in transcriptome sequencing most sequence reads are consumed by mid- and high-abundance transcripts, thus often leaving inadequate coverage of low abundance transcripts [ 4].
These results indicate that some proteins, in most cases probably low-abundance proteins, are still missing in our protein inventory of cells because of the low expression rate of the corresponding genes.
Because of very low expression of ABCA1 and ABCG1 in HEK293T cells, the endogenous levels of ABCA1/ABCG1 were determined after overexpression of p(128) in a dose-dependent manner in HepG2 and MCF7 cells.
PRRNT is very rarely a suitable treatment option for neuroendocrine carcinoma (grade 3), because of the low expression of sstr but it may be considered following the failure of chemotherapy and if In-pentetreotide (OctreoScan) or Ga-DOTATOC/DOTATATE PET/CT demonstrates moderate to high sstr expression.
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because of low inventory
because of low turnout
because of widespread expression
because of creative expression
because of low immunisation
because of low budget
because of low interest
because of low recruitment
because of normal expression
because of low membership
because of low education
because of low fertility
because of low default
because of low demand
because of low pupil
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