Sentence examples for because of linkage with from inspiring English sources

A previous analysis has suggested that this is a Mendelian trait and placed the causal locus on chromosome I because of linkage with the leu2 gene (Sipiczki et al. 1982), but the causal gene remains unidentified.

Despite the long period between date of treatment and date at the end of the study (45 years average, up to 76 years) this study had a high rate of completeness for breast cancer ascertainment because of linkage with the nationwide cancer registries in Sweden and a good number of breast cancer cases available for analysis (n = 245).

"What we've got is confirmation that slavery permeated British society, you can scratch many places and you will find some form of linkage with slavery.

Only rs16890979 is associated with gout in Caucasians [ 7, 11], possibly because of linkage disequilibrium with the more strongly associated intronic variants that include rs6855911 and rs11942223 [ 7, 11].

This may occur because of linkage disequilibrium with an as-yet unidentified gene [39], or because of pleiotropy [36].

Studies of associations between the polymorphisms and cancer risk have been inconsistent, possibly because of linkage disequilibrium with a determinant variant of the XRCC1 gene [ 26].

In this regard, it is interesting to note the likely 'bystander susceptibility effect' for the TGFBR1*6A allele because of linkage disequilibrium with the unknown causative mutation of the allele-specific expression (ASE) in the TGFBR1 gene [ 24].

The most evidence of association was at rs1383264 (P = 2.00 × 10 4) and rs3129716 (P = 1.50 × 10 4), both of which are intergenic in the class II region and so their marginal associations are probably because of linkage disequilibrium with HLA-DQB1 and HLA-DQA1.

Prediction of intrauterine growth disorders represents a compelling challenge for the modern obstetrics because of their linkage with both adverse perinatal outcomes and long-terms effects on good health.

Notably, more than half of the InDels are distributed in genic regions, and these InDels are considered to be genic molecular markers or functional markers (Varshney et al. 2007) that are superior to random DNA markers, such as RFLPs, SSRs and AFLPs, because of complete linkage with trait locus alleles (Andersen and Lübberstedt 2003).

Because of their linkage with ICF/ICF-CY, haemophilia-specific PROs can be used to estimate the prevalence of disability and health in specific patient populations.