Secondary hyperoxaluria is insidious because of its slow progression and may be overseen, particularly in patients with other risks for chronic renal failure such as renal transplant patients.
3 Rosacea represents a therapeutic challenge because of its chronic nature, progression, potential for disfigurement, and psychological impact.
The etiology of rosacea remains unknown and this condition represents a therapeutic challenge because of its chronic nature, progression, potential for disfigurement and psychological impact.
Only observed in the northern hemisphere, and especially in central Europe, Russia/Siberia, Central Asia, Western China, north of Japan, and Alaska, AE is also one among the rare parasitic diseases with a surgical treatment, because of its "tumor-like" progression.
Because of its role in melanoma progression, targeting the MMP-2 antigen by immunotherapy might be particularly effective by limiting the potential selection of antigen loss variants.
Of these four, ADAM9 displayed the largest magnitude of fold change and is of particular interest because of its implication in tumour progression (Duffy et al, 2009).
Although loss of LKB1 by itself may not be sufficient for RCC initiation, it may be important in progression because of its effects on angiogenesis and invasion as demonstrated here.
Because of its strong correlation with disease progression and pain, the peak adduction moment during gait has been identified as a target for treatment design.
We decided to further investigate its methylation profile because of its putative downregulation in PCa progression [31] and observed methylation signal in our cancer/reference dataset (3.2 fold enrichment), suggesting that methylation of this gene may play a role in PCa progression.
Because of its high malignancy and rapid progression, diagnoses are frequently made at an advanced stage.
Thus, whether LTBP3 contributes to tumor progression because of its signaling role or its architectural role remains to be elucidated.
