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Longer incubation times increased the FAR value in untreated cells likely because of induction of DNA strand breaks during incubation.
Although in chemotaxis assays in vitro the mechanisms of leukocyte migration are investigated in the focus of target-oriented cell movement towards a distinct chemoattractant, the study of leukocyte interstitial migration in vivo is limited because of induction of diffuse inflammation in the interstitial tissue [10], [11].
Bosentan decreases effective exposure to warfarin because of induction of CYP3A4 and/or CYP2C9.
It has been suggested that younger patients are more likely to suffer adverse effects because of induction of early menopause and possible infertility [ 12].
It suggests that those early lesions infected with high risk HPV 16 could be induced to progress because of induction of telomerase activity by their E6 oncoprotein.
We hypothesize that the nuclear receptor could be responsible for increased CsA clearance because of induction of CYP3A4 and ABCB1 [ 35, 36].
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It will be of interest for future studies to also determine the down-regulation of this target by miR-199b, even if it appears unlikely because of the lack of induction of apoptosis after miR-199b over-expression in our cellular systems.
No changes were seen in the 6-OHDA/Veh group as expected because of the lack of induction of IL-1β in this group (Fig. 5A).
There was also no evidence of induction of CYP2C19 activity because of Ginkgo biloba treatment [ 38].
High-altitude vineyards receive elevated solar ultraviolet-B (UV-B) levels so producing high quality berries for winemaking because of induction in the synthesis of phenolic compounds.
Case notes were not available for 16 patients, and an additional 23 patients were excluded from analysis because of missing data or because induction of anaesthesia had occurred in another hospital.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com