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Also, tubular dysfunction may occur because of increased chloride delivery to the distal tube.
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Consequently, the association of increasing chloride concentrations with methane concentrations strongly suggests the contribution of a deeper groundwater source with elevated chloride concentrations.
A saturating concentration of clotiazepam (10 μ M) significantly increased chloride currents at GABA EC5−10.
On first inspection the increased chloride suggests the possibility of an unquantified hyperchloremic metabolic acidosis.
The increased chloride concentration in a freshwater aquifer is one of the indicators of seawater intrusion.
Stimulation of TGR5 in biliary epithelial activates the cAMP-regulated chloride channel, CFTR, resulting in increased chloride secretion (Keitel et al. 2009).
In these studies the risk of death increased with increasing chloride levels.
Hypertension develops as a consequence of increased sodium, chloride, and water reabsorption, and subsequent volume expansion.
In cells treated with VCC the extent of increased fluorescence was significantly higher suggesting an increase in chloride permeability.
Indeed, the introduction of chloride increased the rate of Cu release in acetate buffer (Figure 3C).
Coexpression of increasing amounts of GPA cRNA linearly increased the chloride influx of wild-type band 3.
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