Sentence examples for because of inactivation of from inspiring English sources
In hypoxic condition, HIF-1α is stabilized because of inactivation of prolyl hydroxylase.
Transformation upon HPV infection occurs mainly because of inactivation of the p53 and retinoblastoma tumour suppressor proteins mediated by the viral oncoproteins E6 and E7, respectively.
When Rad51p activity is no longer limiting because of inactivation of Srs2p, hybrid formation may overwhelm the anti-hybrid activities of RNases H or Sen1p.
All data presented above point out β-catenin as a major sensor of an array of signals and imply that differentiation defects in tissue homeostasis are likely to underlie tumorigenesis because of inactivation of the APC/ β-catenin signalling pathway.
More importantly, a recent study indicates that the expression of ADAMTS-5 is increased in the articular cartilage of knee joints in adult mice because of inactivation of Sox9.
The intensity of second and further cough efforts gradually decreases, because of inactivation of high-pressure ILM, connected with successive lowering of peak lung volume, peak alveolar pressure, peak abdominal pressure and drive, resulting in lower peak expiratory flow [ 59].
Typically, in the female patient, the cardiac and the muscle involvement showed a patchy distribution because of the pattern of inactivation of the X chromosome [4].
In addition to VILI, controlled mechanical ventilation causes atrophic loss of muscle strength because of inactivation and ventilator-induced diaphragmatic dysfunction (VIDD) [ 3, 4].
The subcutaneous dosing route for consecutive days and reduced bioavailability of 5-azacytidine because of inactivation by cytidine deaminase may limit the expansion of epigenetic therapy into Phase III trials.
Because artificial inactivation of ERK accelerated the timing of apoptosis36, we treated pre-apoptotic eggs with the MEK inhibitor U0126.
Compensation from the unperturbed hemisphere did not explain the lack of an effect, because bilateral inactivation of the PPC caused a minimal decrease in performance (3.6%) that was not significantly different from unilateral inactivations.
