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Because of important misclassifications of exposure, the risk reductions observed in these studies were greatly exaggerated in favor of metformin.
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The use of non-specific definitions of insufficient milk supply likely lead to important misclassification of the exposure.
The small increase so far observed excludes an important misclassification bias of advanced tumours related to the detection at screening.
Because of the misclassifications, the department and federal and state officials have no accurate record of how often minorities are arrested in the city, creating skewed statistics and leading to widespread concern among local civil rights groups.
Because of these possible misclassifications, the observed differences may be underestimations.
A Maine study showed the state lost $18 to $36 million each year in income tax revenues between 1999 and 2002 because of employee misclassification.
This could be because of reduced misclassification of exposure.
Associations may have been underestimated because of nondifferential misclassification resulting from limitations in exposure measurement.
Third, the coded diagnoses may be less well validated than in a prospective survey because of possible misclassification or underreporting.
In a fairly typical Wage and Hour Division case involving a cleaning services company in Chicago, for example, 55 workers were deprived $185,000 in wages because of misclassification.
Moreover, we cannot exclude the possibility of residual confounding and bias because of misclassification.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com