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Because of highly aggressive characteristic, disappointing surgical resection and chemo-radiotherapies, and poor prognosis of the patients with GBC, novel adjuvant therapies or anticancer agents are clearly needed to treat this disease [ 1- 12].
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Andrea Califano and his investigative team discover a molecular signaling mechanism underlying a specific type of highly aggressive breast cancer.
I've heard that there is a species of highly aggressive bees more prone to attack than the typical bee.
T cell non-Hodgkin lymphomas are a heterogeneous group of highly aggressive malignancies with poor clinical outcomes1.
Similarly, a published EMT gene signature30 was also enriched in this group of highly aggressive GBM (Figure 1h).
SRCT comprises a group of highly aggressive malignant tumors [ 13].
The primary tumour -derived BTL1 cells showed chromosomal imbalances typical of highly aggressive glioblastomas.
Although adjuvant therapies have been developed for several types of breast tumors, triple-negative breast cancers (estrogen receptor (ER -, progesterone receptor (PgR)- and human epidermal growth factor receptor 2 (HER2 -negative) are particularly cHER2 -negativetrearebecause of their highly aggressive nature and a lack of well-defined theraparticularlyts on these challenging
The incidence of melanoma continues to rise in western countries, and because of its highly aggressive clinical behaviour and resistance to a wide range of therapies, there are currently no curative treatments once the disease spreads beyond locoregional sites [ 1- 3].
23, 27 The UM-SCC-17B cell line was selected for examination in this model because of its highly aggressive nature and its resistance to radiation therapy, and because it commonly produces tumors in this in vivo model.
Because of its highly aggressive behavior, preoperative neoadjuvant chemotherapy (NAC) has been considered for IMPC [ 6].
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