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Purpose: Surgical control of gastroesophageal reflux (GER) is a challenging problem especially in neurologically impaired children and in acquired GER patients after caustic insult to the esophagus because of high failure rates of the classical antireflux procedures.
While the use of all-metal hips has plummeted in recent years because of high failure rates, surgeons often used the larger ball components because they believed that doing so provided the joint with more rotation and reduced the likelihood of a dislocation.
The discussion came during a review of several initiatives designed to identify classes that are most in demand or needed for degrees but often stymie students because of high failure rates or because too few of the classes are available, among other issues.
Advanced acute respiratory distress syndrome, altered level of consciousness, poor airway protection, and poor patient cooperation are contraindications to noninvasive mechanical ventilation because of high failure rate.
The pharmaceutical industry and the healthcare system are facing major challenges because of high failure rates of drugs, as reported, e.g., for cancer ("High attrition rates-where are we going wrong?" 69.
However, the outcome of metal-on-metal total hip arthroplasty (THA) has been less predictable and some have been withdrawn from the market because of high failure rates [ 9].
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Cementless fixation in total knee arthroplasty (TKA) was introduced to improve the longevity of implants but has yet to be widely adopted because of reports of higher failure rates in some series.
Because of the high failure rate of new drug candidates due to unmanageable toxicity, there is a need for improved approaches for human risk assessment.
Because of the high failure rates of rotator cuff repairs, the methods and materials employed in the surgical repair of rotator cuff tears continues to be an active field of research.
Because of the high failure ratio under conditions of autogamy [ 52], these two species of Bruguiera should have mating systems with high levels of outcrossing.
The bombs are especially dangerous because of their high failure rates, leaving hundreds of the bomblets unexploded on the ground, said Marc Garlasco, a senior military analyst at Human Rights Watch.
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