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If the combination has no advantage or disadvantage because of functional identity of mutant KRAS and EGFR, tumorigenesis should be no different than observed in lines that contain only one of the oncogenes.
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The phenotypic covariance between two individuals given their diploid genotypes is expressed in terms of functional identity states.
We conclude that while the influence of taxonomic structure on ecosystem processes is less important than that of functional identity and diversity, taxonomic composition mediates functional structure.
We suggest that a combined effect of functional identity and functional divergence is the most parsimonious explanation for key ecosystem processes.
Ambiguity still remains however, because depending on the exact biological context, members of a family, however defined, can sometimes be considered as functionally interchangeable and thus worthy of a common functional identity.
Altogether, these results expand our understanding of how gene expression programs determine the functional identity of human tissues.
Because btd is necessary for the maintenance of a type II neuroblast functional identity, we tested whether over-expression of btd is sufficient to induce a type II neuroblast functional identity in a type I neuroblast.
Methodology and the Functional Identity of Science and Philosophy.
This is in agreement with a semantic similarity measure suggesting that 20% of genes change their functional identity over a two-year period37.
This might reveal functional identity of particular marker locus.
More work is needed to confirm the functional identity of these genes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com