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Traditionally, zone 1 and zone 3 injuries were largely managed conservatively because of difficulties relating to surgical access, with surgery reserved for very few, selected cases.
Most prospective studies on endogenous hormones in relation to breast cancer risk have been undertaken among postmenopausal women because of difficulties relating to menstrual timing of sampling among premenopausal women, the relative frequency of postmenopausal and premenopausal breast cancer, and the age spectrum of most established cohorts.
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Although these models readily explained the observed crustal deformation, they were unable to model an offshore fault along the Sagami Trough because of difficulties related to the distance of the offshore fault from the shoreline.
In addition, remanufacturing and recycling options related to the end of life for tires are crucial issues at present because of difficulties related to the degradation of these scrap tires in the environment and the economic benefits of material and energy recovery.
Although he escaped at one point, Adair was unable to reach safety because of difficulties related to his smallpox infection and was recaptured by British Colonel Banastre Tarleton after just three days.
Several attempt to lumbar puncture failed, because of difficulties related to anatomical conformation.
Fourteen patients residing in 32 sparsely populated mountain municipalities were excluded from the analysis because of difficulties related to exposure assessment (see following section).
The sources of difficulties related to information gathering are shown in Fig. 5.
Furthermore, instructors can improve their teaching expertise during the TBL because successful TBL requires that they prepare questions with a certain level of difficulty related to the course content and the specific clinical diagnosis and treatment processes.
These investigations are, however, very labor-consuming, because of the difficulties related to the accessibility of the water surface and its large size.
Because of the difficulties related to Arabic grammar and to the style of Arabic writing, two other Arabic linguistics experts also reviewed the translated version.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com