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However, use of optical imaging techniques in large animals is difficult because of depth limitations.
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For polishing in the semiconductor sector it can be important because of depth-of-focus limitations of photolithography, and the need to maximize silicon useful real-estate.
Further progress required apparatus which could overcome the depth limitation of breathing pure oxygen.
Fluorescence imaging provides a method for detection of specific molecules at subcellular resolution that is potentially superior to conventional imaging modalities; however, it has not been extensively applied in clinical settings, in part because of limitations on penetration depth and excessive background signals.
Depth-of-drilling limitations are inevitable when depths approach or even exceed 1 or 2 km.
Because of the limitations of the data set, in-depth analysis of the reasons for these differences is not apparent.
However, because of staffing limitations these women did not undergo the in-depth interview and detailed information on their sexual assaults was not captured in this study.
I have certain limitations of depth of field with a large camera like this.
This allows for 10 nm axial resolution, but because of the limitations of the current system, imaging is restricted to a relatively thin region at a depth of around 500 nm into the sample [ 14].
Because of data limitations (both temporal: number of years, and spatial: number of WIM sites), more in-depth seasonal variations in truck traffic could not be established with a high confidence level.
The Raid was distinctive because of its limitations.
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