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Other possibilities to further refine the selection of cancer relevant hypermethylated genes are to restrict the ranking to gene promoters that are likely to be methylated because of defined CG-content or the presence of conserved motifs (or similar sequence attributes) related to hypermethylated promoters [ 59- 61].
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High objectivity in implementing the test can be assumed, because of legally defined examination rules.
There is, in one sense, no reality, because the precision of defined personality is washed away.
International comparisons are difficult because a set of defined criteria for reporting is lacking at an international level.
The focus was on the neurons in these regions because of indications of neuronal damage and loss in these regions in mice inhaling brevetoxin 3 (Murray TF, unpublished results) and because of the defined nature of these groups of neurons.
Furthermore, there was no benefit from transfusing RBC whatever the age of blood possibly because of the defined transfusion target (80 90 g/L) or because the poor sensitivity of the tonometric technique[44].
Furthermore, there was no benefit from transfusing RBC whatever the age of blood possibly because of the defined transfusion target (80 90 g/L) or because the poor sensitivity of the tonometric technique [ 44].
The role and importance of bacterioplankton are largely unknown, because of poorly defined taxa and a basic lack of core census information [233].
Primary immunodeficiencies are a group of disorders that are highly amenable to gene therapy because of their defined pathophysiology and the accessibility of the hematopoietic system to molecular intervention.
Disease-specific factors consist of time since diagnosis, smoking habits (smokers, non-smokers, numbers of cigarettes, years smoking), prescribed COPD treatment, number of devices, exacerbations and health care visits because of COPD (defined using patient health centre records).
First, because of the defined criteria used to include studied cases, some of the patients with atypical clinical and laboratory presentations would be missed, e.g. patients without culture-proved bacterial meningitis were not included.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com