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However, when those populations are mixed any signal may be lost because of counteracting effects, depending on how the patient population was mixed.
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Because upregulation of counteracting signaling cascades as a direct response to MEK inhibition limits the efficacy of MEK inhibitors in melanoma patients 23, our results pinpoint the synergistic effect of AAG8 antagonism and MEK inhibition and suggest AAG8 plus MEK inhibitory combination therapy as a potential therapeutic strategy for melanoma.
Yet, because parties are necessarily alliances of disparate constituencies, political scientists have mainly regarded them as a healthy way of counteracting the power of single-issue interest groups.
It is also interesting to note that the T risk allele and the TT risk genotype were present in few centenarians, suggesting that they were not able to foster the T2D phenotype, likely because of being counteracted by healthy lifestyle.
Because of this counteracting influence, the proportion of missing women in the total population has not declined in many countries, including China and India.
As I understand it they think there is no change in depolymerisation activity because of two counteracting effects (increase in activity and decrease in accessibility to the MT ends due to too much lattice binding).
S.U.V.'s roll over three times as often as cars, because they ride higher off the ground and have a higher center of gravity, counteracting the benefit of being bigger.
Early delivery of MSCs probably plays neuroprotective roles because of its counteract against increased toxicity and inflammatory response.
We confirmed Mdm2 mediated the miR-509-5p-induced miR-509-5p-induced miR-509-5p-induced miR-509-5p-inducedf Mdm2 cellteracted the suphenotype effects of miR-509-5p on cell vialterations proliferation in HeLa and QGY-7703 cells.
The pore water pressure also plays a crucial role in the dynamic process of landslide, because it counteracts the normal stresses at the grain contact, and thereby reduces inter-granular friction (George and Iverson 2011).
This is presumably because of enhanced offspring production by immigrant females at the range margins that counteract the low juvenile survival there.
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